Increased femoral anteversion in children – can musculoskeletal modeling better inform clinical decision-making?​

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(Dr. Enrico De Pieri - Senior Research Engineer at Zimmer Biomet and former Research Associate at the University Children's Hospital Basel and Dr. Nathalie Alexander - Head of the Laboratory of Motion Analysis at the Children’s Hospital of Eastern Switzerland in St. Gallen., 15. September, 2023 )

Femoral anteversion refers to the twist between the proximal and distal parts of the femur on the transverse plane. When increased, femoral anteversion does not resolve spontaneously during growth, it can cause disturbances in mobility, altered lower limb kinematics, such as in-toeing gait, functional deficits, and pain. When severe symptoms persist, pediatric and adolescent patients may eventually require an invasive surgical intervention – femoral derotation osteotomy – to correct their altered femoral morphology. Musculoskeletal modeling can help us understand the interplay between altered morphology and kinematics and their association with clinically reported disturbances and complications. In this webcast, Dr. Nathalie Alexander and Dr. Enrico De Pieri will present how personalized musculoskeletal modeling was applied to a cohort of adolescent patients with increased femoral anteversion to answer different clinical questions. Specifically, they investigated whether altered femoral morphology and kinematic deviations represent a risk for joint overloading, lead to altered muscle functionality during gait, and finally, whether surgical intervention can restore these parameters to normative values. They will also illustrate how to compute individual muscle contributions to the net joint moments in the AnyBody Modeling System, which can provide a better understanding of the functional role of different muscles during dynamic tasks.

NB: We apologize for the sound issues experienced during this webinar

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